Thanks for your prompt Reply, I was able to debug the whole thing yesterday, I don't know what to do with this post now though.

Dear Developers,

So I have this Class for a dynamic settings and help interface which works fine see code below. Here are the list of what is not included

Emm Code works for all versions from R21 - S25 Tested

1. I have a .ini file which I read from with a fuction called loadSettings()
2. A replace() fuction which I use to save setting's back to the .ini file
3. a Fuction Called SMsg() which contain' s the message I pass to the replace() for any new message

See how it works in the gif below

it does just that it all works see the code below, After code contains the problem pls scroll down

# ID's

# 1. Main Group That Holds ALl The Other Grooups
ID_MAINGROUP2 = 19000
ID_SUBMAIN = 19500
# 2.LeftBox Group and CheckBox
LB_GROUP = 3000
LB_USE_CUSTOM_COLOR = 3001
LB_TOGGLE_GLOW = 3002
# 3.RighBox Group and COMBObox
COMBO_GROUP = 4000
COMBO_BOXID = 4003
COMBO_USE_ASV = 4004
COMBO_USE_ARV = 4005
# 4. Info
INFO_GROUP = 5000
INFO_TEXTF = 5001

# Ok/Cancle
BTN_GROUP = 7000
BTN_OK          = 7001
BTN_CANCEL      = 7002
# End of ID's
class Settings_Gem(gui.GeDialog):
    """docstring for Settings"""
    def __init__(self):
        super(Settings_Gem, self).__init__()
        self.res = c4d.BaseContainer()

    def InitValues(self):
        print ("Refreshing GUI")
        defaultMSG, Msg1, Msg2, Msg3, Msg4 = SMsg()
        self.AppendGuiHelp(defaultMSG)
        return True

    def AppendGuiHelp(self, msg):

        replace(1, msg)

        # Flush the content of the group that holds all ours SubDialogs
        self.LayoutFlushGroup(INFO_GROUP)

        self.AddMultiLineEditText(INFO_TEXTF, c4d.BFH_SCALEFIT, inith=50, initw=500,
                                  style=c4d.DR_MULTILINE_READONLY | c4d.DR_MULTILINE_WORDWRAP)

        self.GroupEnd()
        # GUISettings,Camera,Comp,Focal,Toggle = loadSettings()
        GUISettings = loadSettings()
        txt = str(GUISettings["setINFO"])
        txtfix = (txt.format("\n"))
        self.SetString(INFO_TEXTF, txtfix)
        # Notifies the content of the MainGroup has changed
        self.LayoutChanged(INFO_GROUP)

        return True
    def CreateLayout(self):
        bc = c4d.BaseContainer() # Initialize a base container
        self.SetTitle("Settings For SetCamS") # Set dialog title
        # ----------------------------------------------------------------------------------------
        self.GroupBegin(ID_MAINGROUP2, c4d.BFH_LEFT, 1, 2)
        self.GroupBorderSpace(5, 5, 5, 5)
        # ----------------------------------------------------------------------------------------
        self.GroupBegin(ID_SUBMAIN, c4d.BFH_FIT | c4d.BFH_LEFT, 4, 1)
        # self.GroupBorderSpace(5, 5, 5, 5)
        # self.GroupBorderNoTitle(c4d.BORDER_ACTIVE_3)

        # Check Box On Left
        self.GroupBegin(LB_GROUP, c4d.BFH_LEFT, 1, 1, "")
        self.GroupBorderNoTitle(c4d.BORDER_ACTIVE_4)
        self.GroupBorderSpace(5, 5, 5, 5)
        self.AddCheckbox(LB_USE_CUSTOM_COLOR, c4d.BFH_LEFT, 0, 13, "Use Custom Color")
        self.AddCheckbox(LB_TOGGLE_GLOW, c4d.BFH_LEFT, 0, 13, "Last Used Show Glow")
        self.GroupEnd()

        # Check Box On Right
        self.GroupBegin(COMBO_GROUP, c4d.BFH_RIGHT, 2, 1, "Cam Mode")
        self.GroupBorder(c4d.BORDER_ACTIVE_4)
        self.GroupBorderSpace(25,13, 25, 13)
        self.AddComboBox(COMBO_BOXID, c4d.BFH_RIGHT, 140, 13)
        self.AddChild(COMBO_BOXID, COMBO_USE_ASV, "Use ASV")
        self.AddChild(COMBO_BOXID, COMBO_USE_ARV, "Use ARV")
        self.GroupEnd() # End 'Alt' group

        self.GroupEnd()

        # Creates a group that will contain all the group representing each tab
        # self.GroupBegin(ID_MAINGROUP, c4d.BFH_SCALEFIT | c4d.BFV_SCALEFIT, 0, 0, '', 0)
        # self.GroupEnd()

        self.GroupBegin(INFO_GROUP, c4d.BFH_RIGHT, 2, 1, "INFO")
        self.GroupBorder(c4d.BORDER_ACTIVE_4)
        self.GroupBorderSpace(5, 3, 5, 3)

        self.AddMultiLineEditText(INFO_TEXTF, c4d.BFH_SCALEFIT, inith=50, initw=500,
                                  style=c4d.DR_MULTILINE_READONLY | c4d.DR_MULTILINE_WORDWRAP)
        # self.SetString(INFO_TEXTF,
        #     "Pls Read!!! \nThis Shows You What Each Setting you Clicked On is Used For."
        #     "\nDon't Ask Why! :| I Am Real Bad At Naming Sh*&"
        #     "\n\nHold CTRL and Run the Script to Ignore All Selected Camera Obj(s), This will Apply any SetCam Script Settings to you C4D Default Camera\n"
        #     "The Default Camera Selected is Based on the ASV/ARV in the Settings GUI.")

        self.GroupEnd()

        self.GroupBegin(BTN_GROUP, c4d.BFH_CENTER, 0, 0, "OK to SaVe Settings") # Begin 'Buttons' group
        self.GroupBorder(2)
        self.AddDlgGroup(c4d.DLG_OK | c4d.DLG_CANCEL)
        self.GroupEnd()

        # Set Defaults
        GUISettings = loadSettings()
        # GUISettings,Camera,Comp,Focal,Toggle = loadSettings()
        txt = str(GUISettings["setINFO"])
        txtfix = (txt.format("\n"))
        self.SetString(INFO_TEXTF, txtfix)
        self.SetInt32(LB_USE_CUSTOM_COLOR,    int(GUISettings['setC_Color']))
        self.SetInt32(LB_TOGGLE_GLOW,     int(GUISettings['setT_Glow']))
        self.SetInt32(COMBO_BOXID,    int(GUISettings['setCOMBO']))


        return True

    def Command(self, id, msg):
        bc = c4d.BaseContainer() # Initialize a base container
        defaultMSG, Msg1, Msg2, Msg3, Msg4 = SMsg()

        #####################
        # Save, Cancle, Esc #
        #####################
        C_Color = int(self.GetInt32(LB_USE_CUSTOM_COLOR)) # Get color
        T_Glow  = int(self.GetInt32(LB_TOGGLE_GLOW)) # Get glow
        Combo   = int(self.GetInt32(COMBO_BOXID)) # Get Camera COMBO

        c4d.gui.GetInputState(c4d.BFM_INPUT_KEYBOARD, c4d.KEY_ESC, bc)
        if bc[c4d.BFM_INPUT_VALUE]:
            print("User Click on ESC")
            self.Close()
            return True

        # User click on Ok button
        if id == c4d.DLG_OK:
            print("User Click on Ok")
            saveSettings(C_Color, T_Glow, Combo)
            self.Close()
            return True

        # User click on Cancel button
        elif id == c4d.DLG_CANCEL:
            print("User Click on Cancel")
            # Close the Dialog
            self.Close()
            return True

        # print (id)

        ############################
        # Staring To Write to File #
        ############################
        if id == LB_USE_CUSTOM_COLOR:
            print ("Settings CustomCOlor")
            self.AppendGuiHelp(Msg1)
            return True

        if id == LB_TOGGLE_GLOW:
            print ("Settings ToggleGlow")
            self.AppendGuiHelp(Msg2)
            return True



        if id == COMBO_BOXID:
            if Combo == COMBO_USE_ASV:
                print ("Settings ASV")
                self.AppendGuiHelp(Msg3)
                return True

            elif Combo == COMBO_USE_ARV:
                print ("Settings ARV")
                self.AppendGuiHelp(Msg4)
                return True

            else:
                print ("WHF")
                self.AppendGuiHelp("Hahaha open a Fucking")


        return True

diag = Settings_Gem()
        diag.Open(c4d.DLG_TYPE_MODAL_RESIZEABLE, 0, -2, -2, 200, 45) # Open dialog

Problem, Now I made a simple popUp dialog and copy pasted the Settings class just as it is and called it

if result == Settings_id:
            diag = Settings_Gem()
    
            diag.Open(c4d.DLG_TYPE_MODAL_RESIZEABLE, 0, -2, -2, 200, 45) # Open dialog

And It's a disaster sometimes I get a
SystemError: error return without exception set "Which is Fustrating"
or worse See gif

The whole thing just Falls Apart I would have pasted the whole code but it's like 2k line plus since it a completion of multiple Things all in one.

Ohh and the .ini File does update only the Gui in cinema4D does not