Thanks so much @m_adam and @Cairyn for your answers!
I'm trying to access the Save checkbox on the left side of the Render Settings panel (marked in red in the image below). I'm able to get and set the Save checkbox under the "Regular Image" area under the Save settings, but can't figure out how to access that master "Save" checkbox. I've searched high and low, but haven't found a way yet. Is that checkbox accessible with Python?
Thanks in advance for any answers!